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Celleron Takes Roche Cancer Drug

UK biopharma Celleron Therapeutics has signed a licensing deal with Roche, gaining exclusive worldwide rights to the Swiss pharma’s monoclonal antibody emactuzumab, which is designed to target and deplete macrophages in solid tumors.

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Australia Inks Vaccine Deal with AstraZeneca

The government of Australia has sealed a deal with AstraZeneca to supply enough doses of the adenovirus vector-based vaccine being developed on behalf of Oxford University to inoculate 95% of the country’s entire population of 25 million. The two sides have signed a Letter of Intentm but details on how the ambitious vaccination plan would be financed have not been revealed.

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Shell Plans Indian Petchems JV

Shell is planning to take a 50% stake and invest up to $9 billion in a petrochemical complex planned by privately held Indian oil company Nayara Energy, according to Reuters news agency.

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BASF to Double Uvinul A Plus Output in Asia

BASF has announced plans to double global capacity for its Uvinul A Plus-branded UV filters with a new line at its Kaohsiung site in Taiwan. Up to now, it has produced the filters solely at its headquarters site in Ludwigshafen, Germany.

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Blackstone Mooted as Buyer for Takeda’s OTC Arm

Japanese pharma Takeda is apparently winding down the asset-shedding drive it launched following the $59 billion acquisition of Shire. The company is currently said to be in talks to sell its domestic consumer health (OTC) business to US private equity investor Blackstone.

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Sanofi Boosts Autoimmune Offering with Principia Buy

Sanofi has agreed to buy US-based Principia Biopharma for $3.68 billion, strengthening its pipeline of treatments for autoimmune disorders. The deal gives the French drugmaker access to Principia’s bruton tyrosine kinase (BTK) inhibitors, which are showing promise in blocking or disrupting the signaling processes that cause inflammation and tissue destruction in autoimmune diseases.

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Is Oleandrin the new Hydroxychloroquine?

As the US death toll from Covid-19 creeps past the 170,000 mark, with a proven vaccine still months away, US president Donald Trump has begun promoting yet another miracle cure for the novel coronavirus. In this case, the focus is on oleandrin, an extract from the oleander plant.

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Nouryon Chooses Green Bay for Expancel Project

Nouryon has revealed Green Bay in Wisconsin, USA, as the site for its Expancel expansion. The Dutch chemicals company announced last year that it planned to hike capacity for the expandable microspheres, but did not reveal a location for the new plant.

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NextChem and GranBio in Ethanol Partnership

Maire Tecnimont’s green chemistry division NextChem has formed a partnership with Brazilian industrial biotech GranBio to co-license the latter’s patented technology to produce second-generation ethanol.

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CureVac Triples Value in Nasdaq Debut

German biotech CureVac has more than tripled its market value to over $5 billion in an initial public offering launched on the US Nasdaq Global Market. Altogether 13.33 million shares changed hands at $16 each, the high end of the offered range. Separately, CureVac is raising €100 million in a private placement.

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Henkel Takes Major Stake in D2C Beauty Brands

Germany’s Henkel has entered into an agreement with compatriot firm Invincible Brands Holding to take a 75% stake in a business that comprises three fast-growing premium direct-to-consumer (D2C) beauty brands: HelloBody, Banana Beauty and Mermaid+Me.

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Momentive Sells Sealants to Henkel, Accelerates Transition

Momentive Performance Materials is selling its consumer sealants business to Henkel for an undisclosed sum in a move the US firm said will enable greater focus on unique silicones and specialty applications where it has “a strong ability to win”.

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Odebrecht Starts Braskem Sale

Brazilian conglomerate Odebrecht has begun the initial process to sell up to its full shareholding in polyolefins producer Braskem. Odebrecht is selling its stake in order to fulfil commitments it made to creditors, both before and during its bankruptcy, Braskem said.

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LGM Pharma Buys Nexgen Assets

US API specialist LGM Pharma has acquired the formulation development and drug product contract manufacturing business of specialty pharma company Nexgen Pharma for an undisclosed sum.

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Austria Invests in Novartis’ Antibiotics Plant

The Austrian government is sharing a third of the cost of a €150 million upgrade Novartis' generics unit Sandoz is stemming at its Kundl, Austria, facility. The Swiss drugmaker claims this is the last remaining integrated production chain for antibiotics in the Western world.

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Pfizer Teams up with Gilead to Make Remdesivir

After teaming up with Germany’s BioNTech to develop a vaccine for Covid-19, US drugs giant Pfizer is joining US Gilead Sciences on the therapeutic side. The biopharma company’s antiviral remdesivir is currently favored as a treatment for the novel coronavirus.

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UK Chemicals Steady in Q2, Uncertainty Ahead

UK chemical exports in the second quarter of this year have steadied but uncertainty looms for the rest of 2020 with risks from both Covid-19 and Brexit, said the Chemical Industries Association (CIA).

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Brenntag Expands in North America

Brenntag has bought the operating assets of US-based Suffolk Solutions’ caustic soda distribution business, gaining access to a bulk terminal and rail transloading facility in the Virginia port city of the same name. The acquired business had sales of about $15.6 million in the fiscal year ending Apr. 30, 2020.

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ADNOC and Wanhua Chemical in Shipping JV

Abu Dhabi National Oil Company (ADNOC)’s shipping and maritime logistics subsidiary ADNOC Logistics & Services (ADNOC L&S) has formed a joint venture with China’s Wanhua Chemical, regarded as the world’s leading producer of polyurethane starting material MDI.

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AstraZeneca Licenses Covid Candidate to China

In a much heeded licensing deal, AstraZeneca (AZ) has awarded Chinese pharma BioKangta sole commercial rights to its AZD1222 Covid-19 vaccine candidate in the People’s Republic. The UK drugmaker is developing the adenovirus vector-based vaccine on behalf of Oxford University, which created it.

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J&J Clinches $1 Billion US Vaccine Supply Deal

Johnson & Johnson (J&J) has struck a deal with the US government worth just over $1 billion to supply 100 million doses of subsidiary Janssen’s SARS-CoV-2 investigational vaccine, Ad26.COV2.S. The terms apply solely to manufacturing of the vaccine in the US but the company suggests it could be distributed worldwide.

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Irregularities Behind Kodak’s API Coup?

Last week’s announcement that photography group Eastman Kodak had received a 25-year, $765 million US government loan to produce active pharmaceutical ingredients (APIs) took the market by surprise. The plan was said to be to secure a national emergency supply, in order to reduce dependence on Chinese and Indian imports.

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Hexion and Poland’s D&R in Resin Collaboration

US thermoset resins and specialty chemicals company Hexion is collaborating with Poland’s D&R Dispersions and Resins on the first commercial-scale production of the former’s VeoVa silane technology, which is free of isocyanates.

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Air Liquide to Take Sasol’s Oxygen Site

Air Liquide and Sasol have entered into exclusive negotiations for the French industrial gases group to acquire Sasol’s oxygen production site in Secunda, South Africa. The move is part of Sasol’s plans to cut CO2 emissions.

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Lonza Expanding Microbial Facility at Visp

Swiss CDMO Lonza is expanding its microbial manufacturing facility in Visp, Switzerland, to add mid-scale (3,000 l) commercial manufacturing for multiple customers and in particular to supply a long-term partner, France’s Laboratoires Servier, with active pharmaceutical ingredients (APIs) for acute lymphoblastic leukemia (ALL) therapies.

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Indian Oil Plans PX/PTA Complex

Indian state-owned oil and gas group Indian Oil Corp will build an integrated paraxylene (PX) and purified terephthalic acid (PTA) complex at Paradip in Odisha, India. Investment costs are estimated at 138 billion Indian rupees, or $1.8 billion.

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Ashland Sells Maleic Anhydride Portfolio to AOC

US chemical producer Ashland said it has reached a “definitive agreement” to sell its maleic anhydride (MA) business and the production plant at Neal, West Virginia, to AOC Materials for $100 million. The transaction is expected to close by the end of 2020, pending all approvals.

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Interview

Navigating Uncertainty and Driving Innovation
Meeting Pharma’s Demand for Speed, Reliability, and Flexibility

Navigating Uncertainty and Driving Innovation

Axplora CCO Arul Ramadurai discusses navigating industry uncertainty, building strategic partnerships, and advancing flexible pharmaceutical manufacturing