22.04.2024 • Sponsored • WhitepaperBioprocessingThermo Fisher

The Power of qPCR in Advancing Cell & Gene Therapy Research

This Expert Insights eBook is designed to enhance scientists’ understanding of qPCR for cell and gene therapy, enabling further research in the field of drug discovery and development.

What you will learn about:

  • Adeno-associated viruses (AAVs)
  • Chimeric Antigen Receptor T-cell (CAR-T) therapy
  • T-cell receptor-engineered T-cell (TCR-T) therapy
  • Advantages of quantitative PCR (qPCR)
  • Identifying qPCR workflows using the QualTrak interactive app
eBook Cover
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More Information

Recent advancements in cell and gene therapy have revolutionized drug discovery and development in the biotech and biopharma sectors. These breakthroughs enable personalized treatments tailored to individual genetic traits and disease profiles, transforming previously untreatable conditions into potential treatment options. As a result, the market for new therapies is expanding, prompting a shift towards personalized medicine and away from generic treatments.

This eBook aims to assist researchers who are interested in learning about the latest developments in gene and cell therapies, including AAV, CAR-T, and TCR-T treatments, along with the crucial role of qPCR technology.

Articles contained in the collection:

  • Tchedre, K.T. et al. (2021). Biodistribution of adeno-associated virus type 2 carrying multi-characteristic opsin in dogs following intravitreal injection. Journal of Cellular and Molecular Medicine. DOI: 10.1111/JCMM.16823.
  • Gokemeijer, J. et al. (2024). An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR-T and TCR-T Cellular Therapies Development. Clinical Pharmacology & Therapeutics. DOI: 10.1002/CPT.3111.

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