25.07.2025 • NewsCROinvestment

Sygnature Discovery Unveils £1 Million Chemistry Facility Upgrade

Sygnature Discovery, an integrated drug discovery contract research organisation (CRO), has completed a major enhancement to its high-throughput chemistry (HTC) capabilities and laboratory infrastructure following a £1 million investment.

high-throughput chemistry equipment
HTC platforms leverage automated systems to efficiently synthesize and purify large volumes of compounds.
© Sygnature Discovery

Sygnature Discovery has doubled the synthesis and purification capacity of its high-throughput chemistry (HTC) platform, now delivering twice the output. The upgrade includes the integration of supercritical fluid chromatography (SFC), making both SFC and reverse-phase purification available. Combined with Sygnature's high-throughput screening (HTS) capabilities, the enhanced HTC platform enables faster compound production and screening, supporting accelerated drug candidate identification.

The upgraded facilities will be fully operational from August and mark a significant milestone in Sygnature’s ongoing growth strategy.

Geraint Jones, Director of Chemistry at Sygnature Discovery, commented: “Our successful track record over the past 20 years on client projects demonstrates our ability to validate robust syntheses and utilize automated processes to deliver high-quality science quickly and efficiently.”

“This investment in our capabilities further enhances the value for our customers and reinforces our commitment to delivering cutting-edge services. Our customers want to partner with a CRO that will help them hit their milestones. This expansion proves we are that partner. We have the facilities, flexibility, and scientific excellence to deliver.”

Company

Logo:

Sygnature Discovery

Bio City, Pennyfoot Street
NG1 1GR Nottingham, Nottinghamshire
UK

Company contact







Interview

Specialty Chemicals in a Shifting World
Adapting to Tariffs and Strengthening Regional Networks

Specialty Chemicals in a Shifting World

Jennifer Abril, President & CEO of SOCMA, discusses the impact of new tariffs and the importance of regional supply networks in the specialty chemical industry.

Whitepaper

Excellence in Pharmaceutical Distribution and The Critical Role of Good Distribution Practice (GDP)
Setting the Standard

Excellence in Pharmaceutical Distribution and The Critical Role of Good Distribution Practice (GDP)

Are you ready to elevate your pharmaceutical operations? Download our exclusive whitepaper and discover how compliance with Good Distribution Practice (GDP) is essential for the safety and integrity of pharmaceuticals.