25.07.2025 • News

Sygnature Discovery Unveils £1 Million Chemistry Facility Upgrade

Sygnature Discovery, an integrated drug discovery contract research organisation (CRO), has completed a major enhancement to its high-throughput chemistry (HTC) capabilities and laboratory infrastructure following a £1 million investment.

high-throughput chemistry equipment
HTC platforms leverage automated systems to efficiently synthesize and purify large volumes of compounds.
© Sygnature Discovery

Sygnature Discovery has doubled the synthesis and purification capacity of its high-throughput chemistry (HTC) platform, now delivering twice the output. The upgrade includes the integration of supercritical fluid chromatography (SFC), making both SFC and reverse-phase purification available. Combined with Sygnature's high-throughput screening (HTS) capabilities, the enhanced HTC platform enables faster compound production and screening, supporting accelerated drug candidate identification.

The upgraded facilities will be fully operational from August and mark a significant milestone in Sygnature’s ongoing growth strategy.

Geraint Jones, Director of Chemistry at Sygnature Discovery, commented: “Our successful track record over the past 20 years on client projects demonstrates our ability to validate robust syntheses and utilize automated processes to deliver high-quality science quickly and efficiently.”

“This investment in our capabilities further enhances the value for our customers and reinforces our commitment to delivering cutting-edge services. Our customers want to partner with a CRO that will help them hit their milestones. This expansion proves we are that partner. We have the facilities, flexibility, and scientific excellence to deliver.”

Company

Logo:

Sygnature Discovery

Bio City, Pennyfoot Street
NG1 1GR Nottingham, Nottinghamshire
UK

Company contact







Interview

The UK Chemical Supply Chain
Trade and Competitiveness

The UK Chemical Supply Chain

The CBA, led by CEO Tim Doggett, is steering the UK chemical supply chain through trade uncertainty, sustainability pressures and logistics challenges, as he explains in this interview with CHEManager.

Article

The State of the US Specialty Chemicals Industry
Reshaping Specialty Chemicals Manufacturing

The State of the US Specialty Chemicals Industry

SOCMA's Jenn Klein examines how specialty chemical manufacturers — the invisible backbone behind pharmaceuticals, electronics, agriculture, and energy — are navigating supply chain shifts, policy uncertainty, and constant change while remaining resilient, disciplined, and focused on execution.

most read

Photo

VCI Welcomes US-EU Customs Deal

The German Chemical Industry Association (VCI) welcomes the fact that Ursula von der Leyen, President of the European Commission, and US President Donald Trump have averted the danger of a trade war for the time being.