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AstraZeneca Covid Vaccine Shows 70% Efficacy

AstraZeneca’s viral vector vaccine candidate for Covid-19, AZD1222, moved back into the spotlight again this week after giving up headlines recently to the mRNA candidates of Pfizer-BioNTech and Moderna.

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Böhringer to Settle More Pradaxa Cases

German privately owned drugmaker Böhringer Ingelheim has reached an agreement in principle to settle nearly 3,000 US lawsuits alleging that its Pradaxa (dabigatran etexilate) anticoagulant drug caused undisclosed bleeding risks. Most of the lawsuits have been filed in the judicial district of Hartford, Connecticut.

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BP and Ineos Launch Hydrogen Projects

BP and Ineos have separately launched clean hydrogen projects as moves toward cutting carbon emissions and meeting the zero carbon emissions targets set by the UN and national governments.

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Pfizer/BioNTech File for Covid Vaccine EUA

As planned, US drugmaker Pfizer and German biotech BioNTech filed an Emergency Use Authorization (EUA) request with the US Food and Drug Administration (FDA) for their mRNA-based Covid-19 vaccine candidate BNT162b2 on Nov. 20.

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CordenPharma Expands non-GMP Peptides

Reacting to recent growth in European domestic demand, Luxembourg-headquartered CordenPharma is expanding capacity for non-GMP peptides at its center of excellence for peptide process development and non-GMP manufacturing in Frankfurt, Germany.

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Croda to Take Iberchem for €820 Million

UK specialty chemical company Croda has agreed to buy Spain’s Iberchem, marking its entry into the flavors and fragrances market. Croda will pay owner French investment group Eurazeo €820 million on a debt-free, cash-free basis.

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Evonik on Track with PA 12 Expansion

German specialty chemicals producer Evonik says it is on track to complete the ongoing €400 million expansion of its PA 12 portfolio as planned, despite a few logistical challenges related to the coronavirus pandemic.

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CureVac Seals Vaccine Supply Deal with EU

German biotech CureVac has signed a supply agreement with the European Commission to provide an initial 225 million doses of its mRNA-based Covid-19 vaccine, with an option for another 180 million doses.

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Achema Will not Take Place in 2021

Achema 2021 will be postponed by almost a year to the beginning of April 2022. The decision to break the 3-year cycle was made in view of the continuing uncertainty caused by the corona pandemic after intensive discussions with the community and in the Achema Committee.

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Croda Supplies Excipients for Pfizer’s Covid-19 Vaccine

UK specialty chemical company Croda International has agreed to supply Pfizer with novel excipients used to make the drugmaker’s Covid-19 vaccine candidate. The contract, which is for a term of five years, enables Croda to initially supply four component excipients for the first three years of the agreement.

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Sasol Starts LDPE Unit at Lake Charles

South African chemical group Sasol has started up the seventh and last plant at its glitch-plagued Lake Charles Chemicals Project (LCCP) in Lake Charles, Louisiana, USA. The 420,000 t/y LDPE facility, which uses ExxonMobil technology, was originally planned to start up in January 2019, but was damaged by an explosion and fire during commissioning.

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Grasim Sells Fertilizer Unit to Indorama

India’s Grasim Industries has agreed to sell its fertilizer business Indo Gulf Fertilisers (IGF) to Indorama India Private, a subsidiary of Singapore’s Indorama Corp., for a cash sum of about $355 million.

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Iktos and Merck Link on AI Drug Design

Iktos, a French company specialized in Artificial Intelligence (AI) for new drug design, has launched a collaboration with German pharmaceuticals, chemicals and life sciences group Merck.

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McDermott Wins Follow-up Russian Cracker Contract

US engineering contractor McDermott International has been awarded a follow-up contract for the ethane cracker complex being built by China National Chemical Engineering & Construction Corporation Seven (CC7) for the Baltic Chemical Plant (BCP) in the Russian Baltic seaport of Ust-Luga.

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W. R. Grace Rejects 40 North Takeover

US specialty chemical company W. R. Grace has rejected a takeover offer by shareholder 40 North Management, stating it “undervalues the company and is not a basis for further discussion.” The offer at $60 per share valued Grace at $4 billion.

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Pfizer-BioNTech Pledge 300 Million Vaccine Doses to EU

US drugmaker Pfizer and its German development partner BioNTech have reached a final agreement with the European Commission to supply 200 million doses of their mRNA-based Covid19 vaccine candidate to the EU’s member states at an undisclosed price.

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Stolt and John T. Essberger in Shipping JV

Stolt Tankers, the wholly owned subsidiary of Norway’s Stolt-Nielsen, has entered into a joint venture with Germany’s John T. Essberger Group to operate a combined fleet of chemical tankers within Europe.

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Thermo Fisher and Innoforce Plan Chinese JV

US scientific equipment manufacturer Thermo Fisher Scientific and China-based CDMO Innoforce have formed a joint venture to own and operate a new pharma services facility for integrated biologics and sterile drug development and manufacturing in Hangzhou, China. Start date for the new entity is 2022.

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ADNOC and ADQ Plan Chemical Projects in Abu Dhabi

Ta’ziz, a joint venture between Abu Dhabi National Oil Company (ADNOC) and compatriot holding company ADQ, will invest more than $5 billion in seven chemical anchor projects and related infrastructure within the planned Ruwais Derivatives Park in Abu Dhabi.

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Lonza Opens new Plant for ADC Payload Manufacturing

Swiss CDMO Lonza has inaugurated the first of two planned state-of-the-art, highly-potent API (HPAPI) suites for antibody-drug conjugate (ADC) drug-linker (payload) manufacturing at its site in Visp, Switzerland. The new facility can handle compounds with occupational exposure levels down to 1ng/m3.

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IMCD to Buy Peak’s Pharma Business

Dutch specialty chemicals and ingredients distributor IMCD has entered into an agreement to buy the pharmaceutical business of compatriot firm Peak International Products for an undisclosed sum.

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Neste and LG Chem Partner on Renewables

Neste and South Korean petrochemicals giant LG Chem have formed a long-term partnership with the aim of developing and growing the global biopolymers and biochemicals market, and more specifically, LG Chem’s domestic market.

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Pfizer-BioNTech Vaccine Claimed 90% Effective

Phase 3 clinical trials with the mRNA vaccine candidate BNT162b2 being developed by US pharma giant Pfizer and German biotech partner BioNTech have shown it to be more than 90% effective in preventing Covid-19 in participants without evidence of prior SARS-CoV-2 infection, the companies announced in a preliminary look at efficacy.

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