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Ingevity Hikes UK Caprolactone Capacity

US specialty chemicals company Ingevity has announced plans to hike capacity for caprolactone monomer at its facility in Warrington, UK. The increase will be achieved through a series of optimization projects over the next 12 months that will expand Ingevity’s global monomer capacity by more than 20%.

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Air Products in Louisiana Clean Energy Project

Industrial gases producer Air Products has announced its largest-ever investment in the US, a $4.5 billion clean energy complex in the state of Louisiana’s Ascension Parish. The company will build, own and operate the mammoth facility expected to go on stream in 2026, producing more than 750 million standard cubic feet (22.5 million cubic meters) per day of “blue” hydrogen and blue ammonia.

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Charles River Sells Assets in Sweden and Japan

US-based Charles River Laboratories International on Oct. 12 completed the divestment of its gene therapy CDMO site in Sweden and its research models and services operations in Japan. The site in Matfors, Sweden, was sold to an unnamed private investor group for about $52 million cash, with potential contingent payments of up to an additional $25 million, subject to certain adjustments.

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A Pivotal Move to Net-Zero

Leading global chemical companies and the World Economic Forum (WEF) have announced that they are entering an agreement to formalize the Low-Carbon Emitting Technologies (LCET) initiative into a stand-alone entity by the end of 2023, to share early-stage risks and co-invest in developing and upscaling low-carbon emitting technologies.

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Bayer Invests in Contraceptives Production

Bayer’s pharmaceuticals division is spending more than €400 million to expand its production facilities for contraceptives in low and middle-income countries, in partnership with international organizations such as the United Nations Population Fund and the United States Agency for International Development.

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Topsoe and Dow Partner on Chemical Recycling

Haldor Topsoe is partnering Dow to accelerate development of chemical recycling technology that converts hard-to-recycle waste plastics into pyrolysis oil feedstock. The Danish group will support the design and engineering of a 10,000 t/y market-development, or pilot, unit to be built at Dow’s site in Terneuzen, the Netherlands.

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Orlen Unipetrol Expands Ethylene Plant

Czech company Orlen Unipetrol, part of Poland’s refining and petrochemicals group PKN Orlen, has announced plans to expand its steam cracker at Litvinov by adding an eleventh furnace. The project costing about 700 million Czech koruna (about €27 million) will expand ethylene output at the site to 585,000 t/y from 545,000 t/y.

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Aceto Acquires A&C Bio Buffer

Virtual specialty materials manufacturer Aceto has acquired A&C Bio Buffer, a GMP manufacturer of custom buffer and chemical blend products used to produce biopharmaceuticals. Financial terms were not disclosed.

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AstraZeneca’s Alexion Buys Caelum Biosciences

AstraZeneca’s rare diseases unit Alexion has taken full control of Caelum Biosciences, gaining access to another rare disease drug, CAEL-101, which is a potential treatment for light chain amyloidosis (AL) that has been granted Fast Track status by the US Food and Drug Administration (FDA).

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Arkema to Build PA Powder Plant in China

French chemical producer Arkema has announced it will build a new plant for bio-based polyamide 11 powder at Changsu, China, with start-up planned for 2023. The investment runs parallel to the company’s €350 million mega project taking shape on Singapore’s Jurong Island, the latter encompassing both a PA resins unit and a plant to produce its feedstock, 11-aminoundecanoic acid.

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CureVac Pulls CVnCov from EMA Approval Process

CureVac is withdrawing its first-generation Covid-19 vaccine candidate, CVnCoV, from the current approval process with the European Medicines Agency. In a statement, the German biotech said the EMA had made it clear that there was no chance of the shot being approved before the second quarter of 2022. By this time, it expects candidates from the second-generation vaccine program it is pursuing with UK drugmaker GlaxoSmitKline (GSK) to have progressed to late-stage clinical development.

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ExxonMobil Studies CCS for Fife Ethylene Plant

ExxonMobil has signed an Expression of Interest for the carbon capture and storage (CCS) of CO2 emissions from its Fife ethylene plant in Scotland. The move sees the US energy and petrochemicals giant increase its participation in the proposed Acorn CCS project, which could potentially store more than 20 million t/y of CO2 by the mid-2030s.

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BASF and Sanyo Partner on PUDs

BASF and Sanyo Chemical Industries have signed a Memorandum of Understanding to jointly develop and produce sustainable polyurethane dispersions (PUDs). The companies said they aim to jointly develop and manufacture innovative products with strong sustainability contribution. Any newly developed technologies and products will have worldwide market access through their global production footprint.

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Merck & Co Files for Oral Covid Antiviral EUA

US pharma giant Merck & Co has applied to the US Food and Drug Administration (FDA) for Emergency Use Authorization (EUA) of its oral antiviral drug molnupiravir, developed together with Ridgeback Biotherapeutics. The New Jersey-based pharma and the Florida-headquartered biotech are positioning the pill as a preventative therapy, rather than as a therapeutic, the latter a path other industry heavyweights are taking.

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Novozymes and Anuvia Partner on Plant Biotech

Danish biotech Novozymes has linked up with US-based Anuvia Plant Nutrients to develop a range of combined biotechnologies to reduce the need for synthetic fertilizers in commercial agriculture. As a first step, the companies will combine Novozymes’ phosphate solubilizing microbial solutions with Anuvia’s bio-based fertilizer products to enhance macronutrient efficiency with a focus on phosphate.

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Dow Taking Big Steps toward Circularity

US chemical giant Dow is pressing ahead with several projects aimed at delivering $3 billion in underlying EBITDA growth as it progresses toward carbon neutrality and circularity. Along with its just announced net-zero carbon emissions ethylene and derivatives complex in Canada, the Midland, Michigan-based group will launch a line of circular plastic solutions and expand its chemical recycling capability.

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Boehringer Inaugurates BioPharma Plant in Austria

Boehringer Ingelheim has inaugurated its Large Scale Cell Culture (LSCC) biopharmaceutical plant at Vienna, Austria. Built over a period of six years at a cost of more than €700 million, the German drugmaker said this is the single largest investment in its history.

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Huntsman Forms Korean Polyurethanes JV

Huntsman has formed a joint venture with South Korean polyols producer KPX Chemical. The jv, named KPX Huntsman Polyurethanes Automotive, will develop and produce polyurethane systems for South Korean automakers from KPX's plant in Ulsan. Operations are expected to start by the end of October.

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Dow Plans Net-Zero Cracker Complex in Canada

Dow has announced plans to build what it regards as the world’s first net-zero carbon emissions ethylene and derivatives complex at its Fort Saskatchewan site in Alberta, Canada. The project, to go on onstream by 2030, will add roughly 1.8 million t/y of ethylene capacity and 3.2 million t/y of PE and ethylene derivatives.

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Bayer Wins its First Roundup Case

Bayer has won its first case in four US lawsuits charging that Monsanto’s glyphosate-based herbicide caused a person’s cancer. A jury in Los Angeles, California, on Oct. 5 rejected a mother’s charge that her spraying Roundup on the family’s property exposed her son to the pesticide and caused him to develop Burkitt’s lymphoma – a form of Non-Hodgkin lymphoma (NHL).

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Kemira Mulls Closure of Pierre-Bénite site

Finnish chemicals company Kemira is evaluating a possible closure of its site in Pierre-Bénite, near Lyon in France. The site, which employs 13 people, produces ferric chloride and different grades of polyaluminium chloride, and was part of Kemira’s acquisition of Arkema’s water treatment business in 2007.

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Evonik Seeking to Sell Lülsdorf Site

Evonik has decided to sell its Lülsdorf site, south of Cologne, Germany, in the medium term. The company said detailed plans for the sale will be finalized by next spring. The goal is to sell the entire site to a new owner, though Evonik said it will consider selling parts of the businesses to “various interested parties.” Employee representatives have been notified of the plans.

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WHO Recommends old GSK Malaria Drug for Africa

The World Health Organization (WHO) has recommended administering GlaxoSmithKline’s 33-year-old malaria vaccine to children across Africa in the hope of stalling the spread of the mosquito-borne disease. Despite a preceding positive recommendation the European Medicines Agency (EMA) in 2015, the vaccine still is not in widespread use.

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Mitsubishi Gas Expands European MXDA Capacity

Mitsubishi Gas Chemical has announced plans to expand capacity for meta-xylenediamine (MXDA) in the Netherlands. The Japanese group said the expansion will meet growth in the European epoxy, polyamide and isocyanate markets.

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Epsilyte Buys StyroChem Canada

Epsilyte Holdings, a leading North American producer of advanced materials used in construction, packaging and safety equipment, has acquired StyroChem, a Canadian expandable polystyrene (EPS) manufacturer, from PMC Capital Partners, which has owned the business since August 2019. Financial terms were not disclosed.

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AstraZeneca Shows FDA Enouraging Antiviral Data

AstraZeneca has provided the US Food and Drug Administration (FDA) with encouraging study evidence that its antiviral cocktail candidate AZD7442 can prevent Covid-19 infections in vulnerable people, such as those who are unlikely to respond well to vaccines. This followed disappointing results from an earlier study.

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EMA Authorizes Covid-19 Booster Shots for All

In a decision not everyone anticipated, the EU’s drugs regulator, European Medicines Agency, EMA, announced on Oct. 4 it was authorizing a booster shot of the Pfizer/BioNTech and Moderna Covid-19 vaccines for healthy adults, to be given at least six months after the second dose.

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Synthos to Build Butadiene Plant at Plock

Polish plastics and rubber producer Synthos is building a new butadiene extrusion unit, coupled with associated logistics infrastructure, at Plock, Poland. The new facility due on stream in 2024 will have an ultimate capacity of 120,000 t/y and will feed the company’s production in central and eastern Europe.

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Thermo Fisher Expands US and Swiss Biologics Capacities

US scientific services supplier Thermo Fisher Scientific is investing $82.5 million to expand operations and create 169 jobs at its biologic drug substance manufacturing plant in St. Louis County, Missouri. The expanded facility will manufacture biologic drug substance products for treating a variety of chronic health conditions, including cancers and other life-threatening diseases, as well as Covid-19.

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IMCD Buys China’s Aquatech

Dutch specialty chemicals and ingredients distributor IMCD has agreed to buy Aquatech Speciality (Shanghai) International Trading and Aquatech Speciality (Guangzhou) Trading in China. No financial details were disclosed for the transaction, which is expected to close during November.

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Merck & Co.’s $11.5 Billion Acceleron Deal May Face Hurdles

US drugs giant Merck & Co. has signed a definitive agreement to acquire publicly traded US biotech Acceleron Pharma for $180 per share, yielding a total equity value of roughly $11.5 billion. Not only because of the size of the transaction, the takeover plans are being closely watched. An activist investor or anti-trust authority could potentially upset the deal, reports suggest.

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