08.12.2015 • NewsDede WillamsEli LillyDiabetes

Eli Lilly to End Peglispro Diabetes Research

US drugmaker Eli Lilly is ending development of its injectable basal insulin peglispro (BIL), a potential treatment for type 1 and type 2 diabetes, to focus on other, more promising, assets in its portfolio and pipeline. The company will take a $55 million pretax charge in the fourth quarter to end the program.

Lilly said late-stage clinical trials with the BIL treatment – a basal insulin taken by patients along with shorter-acting mealtime insulin – had thrown up unresolved questions about changes in liver fat when compared with insulin glargine treatment in the Phase 3 IMAGINE trials. These would require more time and cost more than expected to understand.

Initially, the drugmaker had intended to seek regulatory approval this year, but in February announced a delay.

Enrique Conterno, president, Lilly Diabetes, said that while the research team was encouraged by the efficacy data observed for BIL, “there was no assurance that we would find conclusive answers.” He said Lilly, which has “the industry's broadest diabetes portfolio,” including six new treatments approved since mid-2014, “remains fully committed to innovative research in the diabetes space, including insulins.

Virtual Event

Digitalization in the Chemical Industry
CHEManager Spotlight

Digitalization in the Chemical Industry

Save the Date: October 22, 2025
The event will be promoted to a combined audience of over 100,000 professionals across Europe through the CHEManager and CITplus networks.

Innovation Pitch

The Start-up Platform for Chemistry & Life Sciences
Discover Tomorrow’s Innovators

The Start-up Platform for Chemistry & Life Sciences

CHEManager Innovation Pitch supports innovation in the chemistry and life sciences start-up scene. The platform allows founders, young entrepreneurs, and start-ups to present their companies to the industry.

most read

Photo
27.03.2025 • News

J&J to Invest $55 Billion in US Operations

US healthcare giant Johnson & Johnson (J&J) has unveiled plans to invest over $55 billion in the US over the next four years. This significant investment marks a 25% increase compared to the previous four years, the company said.