21.11.2016 • TopicsalkoxylationBayerEhrfeld Mikrotechnik

Millireactor in Production

Ehrfeld Mikrotechnik BTS designed, manufactured and supplied a MIPROWA...
Ehrfeld Mikrotechnik BTS designed, manufactured and supplied a MIPROWA production reactor for Shaoxing Eastlake Biochemical (China)

Ehrfeld Mikrotechnik BTS designed, manufactured and supplied a MIPROWA production reactor for Shaoxing Eastlake Biochemical (China) for a production capacity of up to 10,000 t/a. The MIPROWA millireactor with a throughput of about 1m3/h has a nominal width of 400 mm and a length of 7 m and contains about 150 rectangular reaction channels with exchangeable static mixers.

Shaoxing Eastlake Biochemical successfully launched the production plant in Shaoxing mid-September. The continuously operated millireactor replaces more than 20 batch reactors. The fast and strong exothermic reaction is of alkoxylation type. Decision for Miprowa technology was driven by achievable product quality, significantly improved yield, safety aspects and a short return on investment. Eastlake serves the global market segment of agrochemicals based on their active ingredients production.

Scale up started from lab scale by a transition of channel geometries from micrometer to millimeter scale. By this proceeding similar conditions could be achieved in lab scale as later in the channels of the production reactor. Furthermore conclusions could be drawn about the performance parameters of the reactor in production scale. Additional validation experiments in pilot scale with same channel geometries as in production were needed for testing real raw material behavior. Compared to established process technologies a much faster scale-up process could be realized.

Whitepaper

Excellence in Pharmaceutical Distribution and The Critical Role of Good Distribution Practice (GDP)
Setting the Standard

Excellence in Pharmaceutical Distribution and The Critical Role of Good Distribution Practice (GDP)

Are you ready to elevate your pharmaceutical operations? Download our exclusive whitepaper and discover how compliance with Good Distribution Practice (GDP) is essential for the safety and integrity of pharmaceuticals.

Interview

Specialty Chemicals in a Shifting World
Adapting to Tariffs and Strengthening Regional Networks

Specialty Chemicals in a Shifting World

Jennifer Abril, President & CEO of SOCMA, discusses the impact of new tariffs and the importance of regional supply networks in the specialty chemical industry.

most read

Photo
19.03.2025 • TopicsStrategy

Substances of Concern

The EU Chemicals Strategy for Sustainability (CSS) highlights the shift to a hazard-centric approach in EU chemical regulation, emphasizing 'Substance of Concern' over risk-based measures.

Photo
14.05.2025 • TopicsPharma

Pharma Outlook 2025

The environment for pharma in 2025 is diverse and challenging: New treatment options are being brought to market in ever shorter cycles.