25.08.2025 • Sponsored • TopicsBiesterfeldPharmaceuticalenvironment

Advanced Intermediates in Pharmaceutical Production

How the Right Partner Can Help Navigate a Challenging Environment

The pharmaceutical industry is evolving due to new regulations and technological developments. Distributors like Biesterfeld play a central role in supporting manufacturers in their daily operations. With their in-depth market knowledge, quality and regulatory expertise, and pan-European logistics and supply chain network, they are major contributors to future success in a competitive global economy.

Competence in Solutions

Advanced intermediates are key building blocks in the pharmaceutical manufacturing process. These complex chemical compounds are produced during the early or mid-stages of drug synthesis and are essential for creating active pharmaceutical ingredients (APIs). By streamlining the production process and ensuring consistent quality, advanced intermediates are vital for improving efficiency, reducing costs, and meeting regulatory standards in drug development and large-scale manufacturing.
With more than 100 years of international expertise, Biesterfeld is one of the leading distributors of specialty chemicals worldwide. Advanced Intermediates is one of four segments — alongside Pharma, Medical, and Animal Health — within the global HealthCare Business Unit.

“Currently, we offer more than 180 registered fine chemicals and advanced intermediates in our portfolio. This includes pyridines and piperidines, ketene derivatives, phase-transfer catalysts, fluorine compounds, and others, as well as customer-specific products for a wide range of applications and market segments,” says Fritjof Weidner, Business Manager Advanced Intermediates at Biesterfeld.
“With our close relationships with innovative partners, a strongly expanded presence in Asia, and our market expertise and knowledge, we can meet current market demands with our flexible product portfolio — which we are able to customize whenever required.”

Advanced Intermediates in Pharmaceutical Production
© Biesterfeld

Partnering with a REACh-Compliant Distributor

Biesterfeld focuses on complex and highly specialized chemical substances. Thanks to in-depth knowledge of customer requirements, Biesterfeld can supply the right product — with the quality, packaging, and delivery time demanded by each specific application.
An experienced distributor functions as a reliable partner, serving its customers along the entire value chain through a well-developed international sales and logistics network. This includes full transparency, compliance, and regulatory support — such as REACh.

REACh (Registration, Evaluation, Authorisation and Restriction of Chemicals) is a key regulation in the European Union, aimed at ensuring the safe use of chemicals in the pharmaceutical industry. A REACh-compliant distributor helps pharmaceutical manufacturers stay legally compliant, maintain supply chain integrity, and secure market access within the EU. This is critical given the strict regulatory environment in pharmaceuticals and the potential consequences of non-compliance.

Securing the Future with the Right Partner Network – Biesterfeld is by Your Side

A strong network of experienced players in the pharmaceutical sector is essential for a successful and sustainable setup in this demanding industry. An experienced distributor can act as a link between manufacturers, regulatory authorities, and healthcare providers, supporting the entire process from purchasing to delivery.

A partner like Biesterfeld stands by its customers’ side with a team of specialized product and marketing experts, quality and regulatory managers, and local sales representatives in all key markets worldwide.

Visit us at CPhI in Frankfurt
October 28–30, at Booth 8OS64, and let’s discuss how Biesterfeld can support you best!

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Biesterfeld AG

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20095 Hamburg
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