Navigating the Logistics Impact
Cell and gene therapies (CGTs) present a revolutionary approach to the pharmaceutical industry. However, several complexities do arise on a logistical spectrum that diverge from those of traditional pharmaceuticals.
News
Integrated Continuous Manufacturing in Pharmaceuticals
An innovative manufacturing platform called integrated continuous manufacturing (ICM) represents a completely modernized model for drug manufacturing. In contrast to batch processes, ICM’s unique operational advantages will allow for cost-competitive end-to-end manufacturing and enable a more robust and responsive supply chain for critical drugs.
A New Standard of Collaboration for the Pharmaceutical Industry
Headquartered in Cramlington, UK, Sterling Pharma Solutions is a contract development and manufacturing organization (CDMO) that provides a range of services to the global biopharmaceutical industry, including active pharmaceutical ingredient (API) development, scale-up and cGMP manufacturing, as well as antibody drug conjugate (ADC) R&D and clinical-scale GMP manufacturing.
The Future of mRNA Technology
mRNA-based vaccines against the coronavirus have become firmly established in medicine since the pandemic. Nevertheless, the technology is still at the beginning of its potential. Experts see a wide range of potential applications for this relatively new technology, particularly in infectious diseases and cancer.
Sustainability and Energy Efficiency at a Turning Point
Flow chemistry was named as one of the ten technologies that have the potential to make our planet more sustainable in 2019 by the IUPAC.
Sustainability in Production is Key - What Does Flow Chemistry Bring to the Table?
Numerous articles have been published within the last years in chemical science and business media (including this one) on the advantages of continuous reactions, aka flow chemistry.
AI-Powered Knowledge Transfer in Manufacturing
Artificial intelligence (AI) can help companies in the process industry capture, retain and access valuable historical expertise and ease the transition for new colleagues in the plant.
2024 Guidance Suspended: API Production Paused in Brindisi, Italy
EuroAPI today announces that its Italian subsidiary, EuroAPI Italy S.R.L., is suspending the production of all APIs (active pharmaceutical ingredients) in Brindisi.
Generative AI in Chromatographic Analysis
Generative AI can impact the field of chromatography in various innovative ways. However, great care needs to be taken to validate any use of this emerging technology from a technical, quality and regulatory perspective.
Roquette Strategically Acquires IFF Pharma Solutions
Roquette, a plant-based ingredients and pharmaceutical excipients manufacturer, announced today an agreement to acquire IFF Pharma Solutions, an excipients for oral dosage solutions producer, to reinforce its position as a major partner to the pharmaceutical industry.
Noncanonical Amino Acids Made by Enzymes
Aralez Bio, a San Francisco-based start-up, has engineered a platform of enzymes that creates 100 times more compound diversity using processes that are also 50 times greener than conventional methods.
High Dynamics in the Supply Chain
Interview with Markus Mau, President of the ELA, about developments for the logistics sector.
Revolutionizing Green Chemical Production with Ultrasound
Biorefining allows low-carbon feedstocks – such as lignocellulosic biomass – to be processed into intermediate chemicals that can be made into renewable plastics for the automotive industry. Sonichem has developed a breakthrough biorefinery technique that uses ultrasonic energy alongside mild organic acids to fractionate softwood sawdust into hemicellulose sugars, microcrystalline cellulose and high-quality lignin.
Digital Twin Meets General Cargo Logistics
The logistics industry urgently needs digital transformation to ensure quality and to tackle challenges such as the shortage of skilled workers and sustainability.
Ecorich Solutions – Turning waste into food
African start-up Ecorich Solutions uses an innovative technology called “the Wastebot decomposer machine” to convert organic waste into organic fertilizer. The process involves the breakdown of organic waste using soil based microbial enzymes under a temperature regulated mechanism.
Partex and Sanofi Partner for AI-Enhanced Dossier Improvement
Partex Group, an AI-driven drug discovery company, today announces a collaboration with global pharmaceutical company Sanofi, aimed at using Partex’s AI technology to enhance the value of Sanofi's out-licensing portfolio.
Chemlink Specialities and Addi-Tec Form Harke UK
Germany-headquartered chemical distributor Harke Group announced that its subsidiaries Chemlink Specialities and Addi-Tec have merged and rebranded as Harke UK, effective Feb.1, 2024.
Noramco Creates North American Pharma Supply Chain Services Provider
Noramco, a US producer of active pharmaceutical ingredients (APIs), has announced the launch of Noramco Group as an integrated North American-based API and drug product supply chain services provider. The strategic alignment includes subsidiaries Purisys, Noramco, and the newly acquired drug product CDMO, Halo Pharma.
AstraZeneca to Buy Amolyt Pharma for up to $1.05 Billion
Britain's AstraZeneca is to acquire Amolyt Pharma, a clinical-stage biotechnology company focused on developing novel treatments for rare endocrine diseases, more than $1 billion.
Antheia and Olon Continue Biomanufacturing Partnership
US biotech company Antheia and Olon, an Italian producer of active pharmaceutical ingredients (APIs), have announced the continuation of their ongoing partnership to utilize Olon’s fermentation infrastructure for the scale-up and commercialization of Antheia’s early products.
Trinseo to Sell Its Share in Americas Styrenics
US specialty materials producer Trinseo has commenced a sale process for its 50% ownership in Americas Styrenics (AmSty), a joint venture (JV) with Chevron Phillips Chemical.
Sasol Appoints Antje Gerber as New Chemicals EVP
Sasol has appointed Antje Gerber as executive vice president Chemicals and member of the group executive committee, effective April 15, 2024. She will succeed Brad Griffith, who is to retire on June 30, 2024.
Adare to Expand Oral Dose Capabilities in Italy
US CDMO Adare Pharma Solutions is to add a high-shear mixer granulator at its Pessano, Italy facility, to complement existing fluid bed capabilities. The new mixer can provide wet granulation using either aqueous or organic-based solutions.
Kyowa Kirin to Build First US Pharma Operations
Japan-based pharmaceutical company Kyowa Kirin plans to build a $200 million biologics manufacturing center in Sanford, North Carolina, creating 102 jobs. This will be the company’s first North American pharmaceutical manufacturing operation, expected to create 102 jobs.
SK Bioscience to Expand South-Korean Vaccine Production Capacity
South Korea-based contract development and manufacturing organization (CDMO) SK Bioscience has broken ground on an approximately 4,200 m2 expansion of its L House vaccine manufacturing facility in Andong, Gyeongsangbuk-do, South Korea, which will serve as the production base for pneumococcal conjugate vaccine candidate GBP410, jointly developed by SK Bioscience and Sanofi, who are co-investing in the expansion.
Sandoz Acquires Ophthalmology Franchise from Coherus
In a move to expand its ophthalmic platform, Sandoz, the former generics and biosimilars arm of Swiss drugmaker Novartis, has completed the acquisition of Coherus BioSciences’ subsidiary Coherus Ophthalmology for $170 million.
AstraZeneca Plans £650 Million Investment in UK
AstraZeneca, whose CEO Pascal Soriot has been critical of the UK business environment for the life sciences industry in the past, wants to invest a large sum at its homebase. On Mar. 6, Chancellor Jeremy Hunt announced that the pharma giant plans to invest £650 million in the UK.
Perstorp Becomes Sole Owner of Chinese Joint Venture
Swedish chemical producer Perstorp has bought out its minority partner in the joint venture (JV) Shandong Perstorp Chemical Co. (formerly Shandong Fufeng Perstorp Chemical Co.), which has owned and operated the site in China. Perstorp is now the sole owner of the polyol manufacturing operation, located in Zibo, Shandong province.
Breakthrough Supply Chains for the Pharmaceutical Industry
The pharmaceutical industry is a truly global and complex network of ingredients and materials suppliers, manufacturers, distributors for a variety of products ranging from vaccines to antibiotics and to therapeutic drugs for customers/patients.
AkzoNobel Completes Capacity Expansion at Vietnam Multi-site
AkzoNobel has completed a significant investment project at its production facility in Bac Ninh province, Vietnam, aimed at strengthening the company’s position in Asia and focusing on more sustainable manufacturing. The total investment amounts to €18.5 million.
Large-Scale Production Announced by Epsilogen and Lonza for Ovarian Cancer Treatment
Epsilogen and Lonza have successfully completed the manufacturing of a potential cancer treatment. The complex process, which took less than ten months, was carried out at Lonza’s UK site following Good Manufacturing Practice (GMP) standards.
ADNOC Completes Acquisition of 24.9% Stake in OMV
Abu Dhabi National Oil Company (ADNOC) has completed the acquisition of a 24.9% stake in Austrian energy group OMV from Mubadala, the sovereign wealth fund of the United Arab Emirates. Financial details of the transaction, which was announced in December 2022, were not disclosed.
Novo Nordisk and Neomorph to Develop Molecular Glue Drugs
US biotechnology company Neomorph signed a $1.46 billion licensing agreement with Novo Nordisk to discover, develop and commercialize molecular glue degraders.
BMS to Invest $400 Million in Expansion of Dublin Site
Bristol Myers Squibb (BMS) wants to invest $400 million for the construction and design of a sterile drug product (SDP) facility at its Cruiserath campus in Dublin, Ireland, significantly expanding manufacturing and laboratory capacity at the site.
AkzoNobel Opens Paints and Coatings Plant in Pakistan
Dutch paints and coatings group AkzoNobel has been opened a new €26 million manufacturing plant Faisalabad, Pakistan – the company’s largest investment in the country to date.
